Crystal structure of (RS)-4-(3-carboxy-1-ethyl-6,8-difluoro-4-oxo-1,4-dihydroquinolin-7-yl)-2-methylpiperazin-1-ium 3-carboxy-5-fluorobenzoate
In the title organic salt, C17H20F2N3O3+·C8H4FO4−, proton transfer leads to one protonated lomefloxacin molecule (HLf+) and one 3-carboxy-5-fluorobenzoate (5-F-Hip−) anion in the asymmetric unit. The HLf+ cation is bent, with a dihedral angle of 38.3 (1)° between the quinoline ring and the piperazin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2019-01-01
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| Series: | Acta Crystallographica Section E: Crystallographic Communications |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2056989018016961 |
| Summary: | In the title organic salt, C17H20F2N3O3+·C8H4FO4−, proton transfer leads to one protonated lomefloxacin molecule (HLf+) and one 3-carboxy-5-fluorobenzoate (5-F-Hip−) anion in the asymmetric unit. The HLf+ cation is bent, with a dihedral angle of 38.3 (1)° between the quinoline ring and the piperazinium moiety. In the crystal, two kinds of N—H...O and O—H...O hydrogen-bonded chains cross-link each other to produce a three-dimensional network structure that is additionally stabilized by weak C—H...O and C—H...F hydrogen bonds, as well as π–π interactions. The methyl group attached to the piperazinium ring is disordered over two sets of sites [refined ratio: 0.645 (5):0.335 (5)], indicating the presence of both enantiomers of the cation in the structure. |
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| ISSN: | 2056-9890 |