A simple adeno-associated virus-based approach for the generation of cardiac genetic models in rats [version 1; peer review: 2 approved]

Background: Heart failure is a major health problem and progress in this field relies on better understanding of the mechanisms and development of novel therapeutics using animal models. The rat may be preferable to the mouse as a cardiovascular disease model due to its closer physiology to humans a...

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Bibliographic Details
Main Authors: Michal Schlesinger-Laufer, Guy Douvdevany, Lilac Haimovich-Caspi, Yaniv Zohar, Rona Shofty, Izhak Kehat
Format: Article
Language:English
Published: F1000 Research Ltd 2020-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-1441/v1