Thermodynamic and kinetic stabilization of divanadate in the monovanadate/divanadate equilibrium using a Zn-cyclene derivative: Towards a simple ATP synthase model

Thermodynamic and kinetic stabilization of divanadate in the monovanadate/divanadate equilibrium using a Zn-cyclene derivative: Towards a simple ATP synthase model

For the condensation of anions such as phosphate and ADP to form ATP and water, nature employs sophisticated supramolecular systems to overcome coulomb repulsion and activation barriers. For an attempt to create a simple, analogous chemical system, the dimerization of vanadate is probably the simple...

Full description

Bibliographic Details
Main Authors: Hanno Sell, Anika Gehl, Frank D. Sönnichsen, Rainer Herges
Format: Article
Language:English
Published: Beilstein-Institut 2012-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
EXSY NMR
NMR titration
supramolecular chemistry
vanadate condensation
51V NMR
Zn-cyclene
Online Access:https://doi.org/10.3762/bjoc.8.8
Description
Summary:For the condensation of anions such as phosphate and ADP to form ATP and water, nature employs sophisticated supramolecular systems to overcome coulomb repulsion and activation barriers. For an attempt to create a simple, analogous chemical system, the dimerization of vanadate is probably the simplest model. We have investigated Zn-benzylcyclene which favors the dimerization thermodynamically as shown by NMR titration. Moreover, EXSY NMR experiments reveal that the vanadate dimer is also kinetically stabilized with respect to hydrolysis by complexation with Zn-cyclene.
ISSN:1860-5397

Similar Items