The power-proportion method for intracranial volume correction in volumetric imaging analysis

The power-proportion method for intracranial volume correction in volumetric imaging analysis

In volumetric brain imaging analysis, volumes of brain structures are typically assumed to be proportional or linearly related to intracranial volume (ICV). However, evidence abounds that many brain structures have power law relationships with ICV. To take this relationship into account in volumetri...

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Bibliographic Details
Main Authors: Jane S. Paulsen, Dawei eLiu, Hans J. Johnson, Jeffrey D Long, Vincent A. Magnotta
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Neuroscience
Subjects:
Magnetic Resonance Imaging
power function
nonlinear model
Intracranial volume
power-proportion correction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00356/full
Description
Summary:In volumetric brain imaging analysis, volumes of brain structures are typically assumed to be proportional or linearly related to intracranial volume (ICV). However, evidence abounds that many brain structures have power law relationships with ICV. To take this relationship into account in volumetric imaging analysis, we propose a power law based method— the power-proportion method—for ICV correction. The performance of the new method is demonstrated using data from the PREDICT-HD study.
ISSN:1662-453X

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