Factors of cardiovascular risk and cognitive dysfunction in patients with controlled hypertension

• Main Author: Krotova V.Yu.
• Format: Article
• Language: English
• Published: SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine" 2016-05-01
• Series: Medičnì Perspektivi
• Subjects: hypertension; risk factors; cognitive dysfunction
• Online Access: http://medpers.dsma.dp.ua/issues/2016/N2/47-52.pdf

According to the survey of 68 patients with arterial hypertension stage II, 1-2 degrees, controlled on the background of antihypertensive therapy, cardiovascular risk, severity of cognitive impairment were analyzed. Instrumental examination of ambulatory blood pressure monitoring; electrocardiography, ultrasound investigation of the main arteries of the head and neck was performed. Neuropsychological examination: an integrated assessment of cognitive functions by MMSE scale; memory evaluation using the procedure of memorizing "Saving 10 words" by Luria; rating of attention and speed of sensorimotor reactions by Schulte and Rybakov procedure was made. Total cardiovascular risk was defined on a scale «SCORE». Typical cognitive disorders in patients with hypertension of working age, even in the controlled blood pressure level were found. Presence of verbal memory disorders associated with hypertension was revealed. The importance of determining the overall cardiovascular risk, diagnosis of cognitive impairment and measuring thickness of the intima-media of the arterial wall as factors of brain lesion which is the target organ in arterial hypertension of 1-2 degrees, was proved.