Upregulation of leukemia inhibitory factor (LIF) during the early stage of optic nerve regeneration in zebrafish.

Upregulation of leukemia inhibitory factor (LIF) during the early stage of optic nerve regeneration in zebrafish.

Fish retinal ganglion cells (RGCs) can regenerate their axons after optic nerve injury, whereas mammalian RGCs normally fail to do so. Interleukin 6 (IL-6)-type cytokines are involved in cell differentiation, proliferation, survival, and axon regrowth; thus, they may play a role in the regeneration...

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Bibliographic Details
Main Authors: Kazuhiro Ogai, Ayaka Kuwana, Suguru Hisano, Mikiko Nagashima, Yoshiki Koriyama, Kayo Sugitani, Kazuhiro Mawatari, Hiroshi Nakashima, Satoru Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4146584?pdf=render

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http://europepmc.org/articles/PMC4146584?pdf=render

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