Computer modeling of hippocampal CA1 pyramidal cells - a tool for in silico experiments

Objective. In silico experiments use mathematical models that capture as much as possible from the properties of the biological system under investigation. Our aim was to test the publicly available CA1 pyramidal cell models using the same simulation tasks, to compare them, and provide a systematic...

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Bibliographic Details
Main Authors: Metz Júlia, Szilágyi T., Perian M., Orbán-Kis K.
Format: Article
Language:English
Published: Sciendo 2015-03-01
Series:Acta Medica Marisiensis
Subjects:
Online Access:https://doi.org/10.1515/amma-2015-0012
Description
Summary:Objective. In silico experiments use mathematical models that capture as much as possible from the properties of the biological system under investigation. Our aim was to test the publicly available CA1 pyramidal cell models using the same simulation tasks, to compare them, and provide a systematic overview of their properties in order to improve the usefulness of these models as a tool for in silico experiments.
ISSN:2247-6113