Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine

Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine

Efficacious vaccines are needed to control genital chlamydial diseases in humans and the veterinary industry. We previously reported a C. abortus (Cab) vaccine comprising recombinant Vibrio cholerae ghosts (rVCG) expressing the conserved and immunogenic N-terminal region of the Cab polymorphic membr...

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Bibliographic Details
Main Authors: Shakyra Richardson, Fnu Medhavi, Tayhlor Tanner, Stephanie Lundy, Yusuf Omosun, Joseph U. Igietseme, Darin Carroll, Francis O. Eko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Chlamydia abortus
Pmp18D
vaccine delivery
Flt3L
adjuvant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.698737/full

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