Mutations in the Mitochondrial ND1 Gene Are Associated with Postoperative Prognosis of Localized Renal Cell Carcinoma

Mutations in the Mitochondrial ND1 Gene Are Associated with Postoperative Prognosis of Localized Renal Cell Carcinoma

We analyzed mutations in the mitochondrial ND1 gene to determine their association with clinicopathological parameters and postoperative recurrence of renal cell carcinoma (RCC) in Japanese patients. Among 62 RCC cases for which tumor pathology was confirmed by histopathology, ND1 sequencing reveale...

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Bibliographic Details
Main Authors: Hakushi Kim, Tomoyoshi Komiyama, Chie Inomoto, Hiroshi Kamiguchi, Hiroshi Kajiwara, Hiroyuki Kobayashi, Naoya Nakamura, Toshiro Terachi
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial DNA
ND1
renal cell carcinoma
prognostic factor
polymorphism
heteroplasmy
nucleotide differentiation index
Online Access:http://www.mdpi.com/1422-0067/17/12/2049

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