Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA

Abstract Liquid biopsy testing utilising Next Generation Sequencing (NGS) is rapidly moving towards clinical adoption for personalised oncology. However, before NGS can fulfil its potential any novel testing approach must identify ways of reducing errors, allowing separation of true low-frequency mu...

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Bibliographic Details
Main Authors: Thomas L. Dunwell, Simon C. Dailey, Anine L. Ottestad, Jihang Yu, Philipp W. Becker, Sarah Scaife, Susan D. Richman, Henry M. Wood, Hayley Slaney, Daniel Bottomley, Xiangsheng Yang, Hui Xiao, Sissel G. F. Wahl, Bjørn H. Grønberg, Hongyan Dai, Guoliang Fu
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82737-9

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