Correction of Bilirubin Conjugation in the Gunn Rat Using Hepatocytes Immobilized in Alginate Gel Beads as an Extracorporeal Bioartificial Liver
A new extracorporeal bioartificial liver using alginate-entrapped hepatocytes was developed and evaluated for its ability to correct the lack of bilirubin conjugation in the Gunn rat. Hepatocytes were harvested from Sprague-Dawley rats by the two-step collagenase perfusion method and then immobilize...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
1993-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368979300200603 |