DNA methylation status of TBX20 in patients with tetralogy of Fallot

DNA methylation status of TBX20 in patients with tetralogy of Fallot

Abstract Background TBX20 plays an important role in heart development; however, its epigenetic regulation in the pathogenesis of tetralogy of Fallot (TOF) remains unclear. Methods The methylation levels of the TBX20 promoter region in the right ventricular myocardial tissues of TOF and control samp...

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Bibliographic Details
Main Authors: Juan Gong, Wei Sheng, Duan Ma, Guoying Huang, Fang Liu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Medical Genomics
Subjects:
DNA methylation
TBX20 gene
Sp1 transcription factor
Tetralogy of Fallot
Online Access:http://link.springer.com/article/10.1186/s12920-019-0534-3

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http://link.springer.com/article/10.1186/s12920-019-0534-3

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