Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line

Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line

The alternative splicing of pre-mRNAs expands a single genetic blueprint to encode multiple, functionally diverse protein isoforms. Viruses have previously been shown to interact with, depend on, and alter host splicing machinery. The consequences, however, incited by viral infection on the global a...

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Bibliographic Details
Main Authors: Gaston Bonenfant, Ryan Meng, Carl Shotwell, Pheonah Badu, Anne F. Payne, Alexander T. Ciota, Morgan A. Sammons, J. Andrew Berglund, Cara T. Pager
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
Zika virus
Flavivirus
SH-SY5Y
transcriptome
alternative splicing
Online Access:https://www.mdpi.com/1999-4915/12/5/510

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https://www.mdpi.com/1999-4915/12/5/510

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