In Vitro Metabolism of Dibenzo[a,l]pyrene, 2-Chlorodibenzo [a,l]pyrene and 10-Chlorodibenzo[a,l]pyrene - Effects of Chloro Substitution

In Vitro Metabolism of Dibenzo[a,l]pyrene, 2-Chlorodibenzo [a,l]pyrene and 10-Chlorodibenzo[a,l]pyrene - Effects of Chloro Substitution

Abstract: Stereoselective metabolism of dibenzo[a,l]pyrene (DB[a,l]P), 2-chlorodibenzo[a,l]pyrene (2-Cl-DB[a,l]P) and 10-chlorodibenzo[a,l]pyrene (10-Cl-DB[a,l]P) by rat liver microsomes was studied and effects of the chloro substituent on the metabolism were determined. All three compounds produced...

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Bibliographic Details
Main Authors: Hongtao Yu, Huey-Min Hwang, Peter P. Fu, Linda S. Von Tungeln, Joanna Moody, Guor-Cheng Fang, Yuh-Shen Wu
Format: Article
Language:English
Published: MDPI AG 2002-09-01
Series:International Journal of Molecular Sciences
Subjects:
Microsomal metabolism
dibenzo[a
l]pyrene
2-chlorodibenzo[a
l] pyrene
10- chlorodibenzo[a
Online Access:http://www.mdpi.com/1422-0067/3/9/1008/

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