NAIGO: An Improved Method to Align PPI Networks Based on Gene Ontology and Graphlets

NAIGO: An Improved Method to Align PPI Networks Based on Gene Ontology and Graphlets

With the development of high throughput technologies, there are more and more protein–protein interaction (PPI) networks available, which provide a need for efficient computational tools for network alignment. Network alignment is widely used to predict functions of certain proteins, identify conser...

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Bibliographic Details
Main Authors: Lijuan Zhu, Ju Zhang, Yi Zhang, Jidong Lang, Ju Xiang, Xiaogang Bai, Na Yan, Geng Tian, Huajun Zhang, Jialiang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
PPI network
network alignment
gene ontology
graphlets
functional ortholog
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00547/full

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