Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning

Overexpression of activated CaMKII in the CA1 hippocampus impairs context discrimination, but not contextual conditioning

Abstract Calcium/Calmodulin-dependent protein kinase II (CaMKII) plays a key role in the molecular mechanism of memory formation. CaMKII is known to be activated specifically in the activated spines during memory formation. However, it is unclear whether the specific activation of CaMKII is necessar...

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Bibliographic Details
Main Authors: Sanghyun Ye, Ji-il Kim, Jooyoung Kim, Bong-Kiun Kaang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Brain
Subjects:
Context discrimination
CaMKII
Hippocampus
Memory
Contextual fear conditioning
Online Access:http://link.springer.com/article/10.1186/s13041-019-0454-3

Internet

http://link.springer.com/article/10.1186/s13041-019-0454-3

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