Mechanism of KLF4 Protection against Acute Liver Injury via Inhibition of Apelin Signaling

Krüppel-like factor 4 (KLF4) is a key transcription factor that regulates genes involved in the proliferation or differentiation in different tissues. Apelin plays roles in cardiovascular functions, metabolic disease, and homeostatic disorder. However, the biological function of apelin in liver dise...

Full description

Bibliographic Details
Main Authors: Weitao Ji, Hongyun Shi, Hailin Shen, Jing Kong, Jiayi Song, Hongyan Bian, Xinrui Lv
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/6140360