OnabotulinumtoxinA in the treatment of neurogenic bladder

OnabotulinumtoxinA in the treatment of neurogenic bladder

Aziz Gulamhusein, Altaf MangeraDepartment of Urology Research, Sheffield Teaching Hospitals NHS Trust, Royal Hallamshire Hospital, Sheffield, United KingdomAbstract: This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since...

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Main Authors: Gulamhusein A, Mangera A
Format: Article
Language:English
Published: Dove Medical Press 2012-08-01
Series:Biologics : Targets & Therapy
Online Access:http://www.dovepress.com/onabotulinumtoxina-in-the-treatment-of-neurogenic-bladder-a10842
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spelling doaj-fb955cee469248cdbbf9caff8b788a892020-11-24T23:50:57ZengDove Medical PressBiologics : Targets & Therapy1177-54751177-54912012-08-012012default299306OnabotulinumtoxinA in the treatment of neurogenic bladderGulamhusein AMangera AAziz Gulamhusein, Altaf MangeraDepartment of Urology Research, Sheffield Teaching Hospitals NHS Trust, Royal Hallamshire Hospital, Sheffield, United KingdomAbstract: This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since its first use in 1988 to treat detrusor sphincter dyssynergia, use of botulinum toxin has increased in this group of patients. We discuss the mechanism of action, patient selection, dosing, efficacy, and side effect profile of this now licensed treatment option.Keywords: neurogenic bladder, botulinum toxin, onabotulinumtoxinA, neurogenic detrusor overactivity, detrusor sphincter dyssynergiahttp://www.dovepress.com/onabotulinumtoxina-in-the-treatment-of-neurogenic-bladder-a10842
collection DOAJ
language English
format Article
sources DOAJ
author Gulamhusein A
Mangera A
spellingShingle Gulamhusein A
Mangera A
OnabotulinumtoxinA in the treatment of neurogenic bladder
Biologics : Targets & Therapy
author_facet Gulamhusein A
Mangera A
author_sort Gulamhusein A
title OnabotulinumtoxinA in the treatment of neurogenic bladder
title_short OnabotulinumtoxinA in the treatment of neurogenic bladder
title_full OnabotulinumtoxinA in the treatment of neurogenic bladder
title_fullStr OnabotulinumtoxinA in the treatment of neurogenic bladder
title_full_unstemmed OnabotulinumtoxinA in the treatment of neurogenic bladder
title_sort onabotulinumtoxina in the treatment of neurogenic bladder
publisher Dove Medical Press
series Biologics : Targets & Therapy
issn 1177-5475
1177-5491
publishDate 2012-08-01
description Aziz Gulamhusein, Altaf MangeraDepartment of Urology Research, Sheffield Teaching Hospitals NHS Trust, Royal Hallamshire Hospital, Sheffield, United KingdomAbstract: This review examines the evidence for use of onabotulinumtoxinA in the treatment of neurogenic lower urinary tract dysfunction. Since its first use in 1988 to treat detrusor sphincter dyssynergia, use of botulinum toxin has increased in this group of patients. We discuss the mechanism of action, patient selection, dosing, efficacy, and side effect profile of this now licensed treatment option.Keywords: neurogenic bladder, botulinum toxin, onabotulinumtoxinA, neurogenic detrusor overactivity, detrusor sphincter dyssynergia
url http://www.dovepress.com/onabotulinumtoxina-in-the-treatment-of-neurogenic-bladder-a10842
work_keys_str_mv AT gulamhuseina onabotulinumtoxinainthetreatmentofneurogenicbladder
AT mangeraa onabotulinumtoxinainthetreatmentofneurogenicbladder
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