Molecular basis for the dissociation dynamics of protein A-immunoglobulin G1 complex.

Molecular basis for the dissociation dynamics of protein A-immunoglobulin G1 complex.

Staphylococcus aureus protein A (SpA) is the most popular affinity ligand for immunoglobulin G1 (IgG1). However, the molecular basis for the dissociation dynamics of SpA-IgG1 complex is unclear. Herein, coarse-grained (CG) molecular dynamics (MD) simulations with the Martini force field were used to...

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Bibliographic Details
Main Authors: Fu-Feng Liu, Bo Huang, Xiao-Yan Dong, Yan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3680412?pdf=render

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