THE MODULATORY EFFECTS OF INTERLEUKIN-4 AND INTERFERON-GAMMA PRODUCTION BY T-HELPER CELLS ON IgE SYNTHESIS IN CHILDREN WITH ATOPIC DISEASE
Interleukin-4 (IL-4) is produced by T-helper cells type 2 (TH2) and induces IgE synthesis. T-helper cells type 1 (TH1) produce interferon-gamma (IFN-gamma) which suppresses TH2 and reduces IL-4 induced IgE production. In this :;tudy , we demonstrated that the levels of specific IgE in the serum of a...
Main Authors: | Alireza Uungbur, Antonio Pizzulli, Mohammad Javad Marashi, Kiumars Ilaji Nouri, Mansour Kahmani |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2000-04-01
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Series: | Iranian Journal of Allergy, Asthma and Immunology |
Subjects: | |
Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/12 |
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