Design, synthesis, and biological evaluation of novel diclofenac analogs as promising anti-inflammatory agents

Design, synthesis, and biological evaluation of novel diclofenac analogs as promising anti-inflammatory agents

INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesics and antipyretics in the treatment of pain, fever, and rheumatoid arthritis. Major side effect with treatment of NSAIDs is gastric irritation. 1,3,4-thiadiazole is an imperative scaffold since several of these d...

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Bibliographic Details
Main Authors: Manjula K Chikkamath, Girish A Hampannavar, Mahesh B Palkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Health Sciences and Biomedical Research KLEU
Subjects:
1
3
4-thiadiazole
anti-inflammatory activity
Diclofenac
Schiff base
Online Access:http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2019;volume=12;issue=1;spage=35;epage=43;aulast=Chikkamath

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