Reversible N6-methyladenosine of RNA: The regulatory mechanisms on gene expression and implications in physiology and pathology

N6-methyladenosine (m6A) is the most abundant inner RNA modification in eukaryotes. Due to the development of RNA sequencing technology, the distribution pattern of m6A in the transcriptome has been uncovered. Dynamically, the reversible N6-methylation is mediated by two types of proteins, which are...

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Bibliographic Details
Main Authors: Xinyu Fang, Mengyang Li, Tao Yu, Gaoli Liu, Jianxun Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Genes and Diseases
Subjects:
m6A
RNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300842