AFLAP: assembly-free linkage analysis pipeline using k-mers from genome sequencing data

Abstract Our assembly-free linkage analysis pipeline (AFLAP) identifies segregating markers as k-mers in the raw reads without using a reference genome assembly for calling variants and provides genotype tables for the construction of unbiased, high-density genetic maps without a genome assembly. AF...

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Bibliographic Details
Main Authors: Kyle Fletcher, Lin Zhang, Juliana Gil, Rongkui Han, Keri Cavanaugh, Richard Michelmore
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02326-x