Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury

Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury

Spinal cord injury (SCI) induces an immune response during which microglia, the resident immunocompetent cells of the central nervous system, become activated and migrate to the site of damage. Depending on their state of activation, microglia secrete neurotoxic or neurotrophic factors that influenc...

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Bibliographic Details
Main Authors: Jaime Emmetsberger, Stella E. Tsirka
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Neurobiology of Disease
Subjects:
Hemisection
Spinal cord injury
Mice
Microglia
Oligodendrocytes
MIF/TKP
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611200174X

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