The Complexity of TET2 Functions in Pluripotency and Development

The Complexity of TET2 Functions in Pluripotency and Development

Ten-eleven translocation-2 (TET2) is a crucial driver of cell fate outcomes in a myriad of biological processes, including embryonic development and tissue homeostasis. TET2 catalyzes the demethylation of 5-methylcytosine on DNA, affecting transcriptional regulation. New exciting research has provid...

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Bibliographic Details
Main Authors: Vera Garcia-Outeiral, Cristina de la Parte, Miguel Fidalgo, Diana Guallar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TET2
epigenetic
epitranscriptomic
pluripotency
reprogramming
development
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.630754/full

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