Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

Surface enhanced Raman spectroscopy (SERS) and confocal Raman microscopy are applied to investigate the structure and the molecular arrangement of sub-micron furosemide and polyvinylpyrrolidone (furosemide/PVP) particles produced by spray flash evaporation (SFE). Morphology, size and crystallinity o...

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Bibliographic Details
Main Authors: Jakob Hübner, Jean-Baptiste Coty, Yan Busby, Denis Spitzer
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
SERS
Confocal Raman microscopy
Surface characterization
Sub-micron particles
Pharmaceutic composites
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920310960

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http://www.sciencedirect.com/science/article/pii/S2095177920310960

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