Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats

Orellanine is a nephrotoxin found in mushrooms of the Cortinarius family. Accidental intake of this substance may cause renal failure. Orellanine is specific for proximal tubular cells and could, therefore, potentially be used as treatment for metastatic renal cancer, which originates from these cel...

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Bibliographic Details
Main Authors: Deman Najar, Börje Haraldsson, Annika Thorsell, Carina Sihlbom, Jenny Nyström, Kerstin Ebefors
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/10/8/333