IFN-λ1 with Th17 axis cytokines and IFN-α define different subsets in systemic lupus erythematosus (SLE)

IFN-λ1 with Th17 axis cytokines and IFN-α define different subsets in systemic lupus erythematosus (SLE)

Abstract Background Interferon (IFN)-α is thought to have a pivotal role in systemic lupus erythematosus (SLE), and type III IFNs (IFN-λ) were recently also associated with SLE. In this study, we measured levels of IFN-α, IFN-λ1, and related cytokines, such as IL-17A, IL-23, and interferon-γ-induced...

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Bibliographic Details
Main Authors: Vilija Oke, Susanna Brauner, Anders Larsson, Johanna Gustafsson, Agneta Zickert, Iva Gunnarsson, Elisabet Svenungsson
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Interferon-α
Interferon-λ1
Interleukin-17
Interleukin-23
IP-10
Online Access:http://link.springer.com/article/10.1186/s13075-017-1344-7

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