Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Midbrain dopamine (mDA) neurons are significantly associated with Parkinson’s disease and yet there is no systematic molecular classification of these heterogenous group of cells. Here authors use single cell RNA sequencing of isolated mouse neurons expressing the transcription factor Pitx3 (broad m...

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Bibliographic Details
Main Authors: Katarína Tiklová, Åsa K. Björklund, Laura Lahti, Alessandro Fiorenzano, Sara Nolbrant, Linda Gillberg, Nikolaos Volakakis, Chika Yokota, Markus M. Hilscher, Thomas Hauling, Fredrik Holmström, Eliza Joodmardi, Mats Nilsson, Malin Parmar, Thomas Perlmann
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08453-1

Internet

https://doi.org/10.1038/s41467-019-08453-1

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