Do anti-angiogenic VEGF (VEGFxxxb) isoforms exist? A cautionary tale.

Do anti-angiogenic VEGF (VEGFxxxb) isoforms exist? A cautionary tale.

Splicing of the human vascular endothelial growth factor-A (VEGF-A) gene has been reported to generate angiogenic (VEGFxxx) and anti-angiogenic (VEGFxxxb) isoforms. Corresponding VEGFxxxb isoforms have also been reported in rat and mouse. We examined VEGFxxxb expression in mouse fibrosarcoma cell li...

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Bibliographic Details
Main Authors: Sheila Harris, Madeleine Craze, Jillian Newton, Matthew Fisher, David T Shima, Gillian M Tozer, Chryso Kanthou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3342274?pdf=render

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http://europepmc.org/articles/PMC3342274?pdf=render

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