The dynamic properties of angiotensin II type 1 receptor inverse agonists in solution and in the receptor site

The dynamic properties of angiotensin II type 1 receptor inverse agonists in solution and in the receptor site

In this article, the conformational properties of olmesartan and its methylated analogue were charted using a combination of NMR spectroscopy and molecular modeling. For the molecular docking experiments three different forms of angiotensin II type 1 receptor (AT1R) have been used: (a) crystal struc...

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Bibliographic Details
Main Authors: Tahsin F. Kellici, Dimitrios Ntountaniotis, George Liapakis, Andreas G. Tzakos, Thomas Mavromoustakos
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535216302234

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