Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer

Introduction Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament fibroblasts (PDLFs). We hypothesized that metabolic dysfunction of PDLFs in...

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Bibliographic Details
Main Authors: Amal Ashour, Mingzhan Xue, Maryam Al-Motawa, Paul J Thornalley, Naila Rabbani
Format: Article
Language:English
Published: BMJ Publishing Group 2020-12-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/2/e001458.full

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