Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Abstract GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of...
Main Authors: | Brent Wilkinson, Jing Li, Marcelo P. Coba |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05588-3 |
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