Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

Abstract GTPase-activating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases. Several GAPs and GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamatergic neurons and regulate the activity of...

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Bibliographic Details
Main Authors: Brent Wilkinson, Jing Li, Marcelo P. Coba
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05588-3