Combining New Non-Nucleoside Reverse Transcriptase Inhibitors (RTIs) with AZT Results in Strong Synergism against Multi-RTI-Resistant HIV-1 Strains

Combining New Non-Nucleoside Reverse Transcriptase Inhibitors (RTIs) with AZT Results in Strong Synergism against Multi-RTI-Resistant HIV-1 Strains

Reverse transcriptase inhibitors (RTIs), including nucleoside RTIs (NRTIs) and non-nucleoside RTIs (NNRTIs), are critical antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) infection. Emergence of multi-RTI resistance calls for the development of more potent therapeutics or...

Full description

Bibliographic Details
Main Authors: Fei Yu, Wen Li, Lili Wang, Yu Dai, Xin Lu, Qian Wang, Lan Xie, Shibo Jiang
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
HIV-1
HAART
NNRTIs
antiviral activity
combination
synergism
Online Access:http://www.mdpi.com/1420-3049/23/7/1599

Internet

http://www.mdpi.com/1420-3049/23/7/1599

Similar Items