Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication be...

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Bibliographic Details
Main Authors: Romen Rodriguez-Trujillo, Indumathi Vedarethinam, Luigi Sasso, Mark Holm Olsen, Patricia Vazquez, Maria Dimaki, Winnie E. Svendsen
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/10/11/10339/
Description
Summary:In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication between cells and ultimately for brain slice recordings and small nanoelectrodes for highly localized measurements and ultimately for intracellular studies. Electrical and electrochemical characterization of these electrodes as well as the results of PC12 cell differentiation on chip will be presented and discussed.
ISSN:1424-8220