Evaluation of Transduction Properties of an Adenovirus Vector in Neonatal Mice

In gene therapy for congenital disorders, treatments during neonate and infant stages are promising. Replication-incompetent adenovirus (Ad) vectors have been used in gene therapy studies of genetic disorders; however, the transduction properties of Ad vectors in neonates and infants have not been f...

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Bibliographic Details
Main Authors: Shunsuke Iizuka, Fuminori Sakurai, Kahori Shimizu, Kazuo Ohashi, Shin-ichiro Nakamura, Masashi Tachibana, Hiroyuki Mizuguchi
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/685374