Beyond a Ribosomal RNA Methyltransferase, the Wider Role of MraW in DNA Methylation, Motility and Colonization in Escherichia coli O157:H7

Beyond a Ribosomal RNA Methyltransferase, the Wider Role of MraW in DNA Methylation, Motility and Colonization in Escherichia coli O157:H7

MraW is a 16S rRNA methyltransferase and plays a role in the fine-tuning of the ribosomal decoding center. It was recently found to contribute to the virulence of Staphylococcus aureus. In this study, we examined the function of MraW in Escherichia coli O157:H7 and found that the deletion of mraW le...

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Bibliographic Details
Main Authors: Xuefang Xu, Heng Zhang, Ying Huang, Yuan Zhang, Changde Wu, Pengya Gao, Zhongqiu Teng, Xuelian Luo, Xiaojing Peng, Xiaoyuan Wang, Dai Wang, Ji Pu, Hongqing Zhao, Xuancheng Lu, Shuangshuang Lu, Changyun Ye, Yuhui Dong, Ruiting Lan, Jianguo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
E. coli O157:H7
MraW
DNA methylation
motility
intestine colonization
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02520/full

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