Detection of a Low Level and Heterogeneous B Cell Immune Response in Peripheral Blood of Acute Borreliosis Patients With High Throughput Sequencing

Detection of a Low Level and Heterogeneous B Cell Immune Response in Peripheral Blood of Acute Borreliosis Patients With High Throughput Sequencing

The molecular diagnosis of acute Borreliosis is complicated and better strategies to improve the diagnostic processes are warranted. High Throughput Sequencing (HTS) of human B cell repertoires after e.g., Dengue virus infection or influenza vaccination revealed antigen-associated “CDR3 signatures”...

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Bibliographic Details
Main Authors: Josiane Kirpach, Alessia Colone, Jean-Philippe Bürckert, William J. Faison, Axel R. S. X. Dubois, Regina Sinner, Anna L. Reye, Claude P. Muller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
Borrelia
B cell repertoire
Lyme
Borreliosis
VlsE-C6
tetramer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01105/full

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