Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]

Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]

Pharmaceutical and personal care products (PPCPs) are commonly used chemicals that are increasingly detected in urban-impacted environments, particularly those receiving treated wastewater. PPCPs may have toxicological effects on the macrofauna that are exposed through contaminated water; thus, ther...

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Main Authors: Abigail W. Porter, Sarah J. Wolfson, Max Häggblom, Lily Y. Young
Format: Article
Language:English
Published: F1000 Research Ltd 2020-02-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-130/v1
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spelling doaj-fae7082a96bb4b2aab5bfa0ebaef7ddb2020-11-25T03:54:24ZengF1000 Research LtdF1000Research2046-14022020-02-01910.12688/f1000research.21827.124063Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]Abigail W. Porter0Sarah J. Wolfson1Max Häggblom2Lily Y. Young3Department of Environmental Sciences, School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, New Brunswick, NJ, USADepartment of Environmental Sciences, School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, New Brunswick, NJ, USADepartment of Biochemistry and Microbiology, School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, New Brunswick, NJ, USADepartment of Environmental Sciences, School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, New Brunswick, NJ, USAPharmaceutical and personal care products (PPCPs) are commonly used chemicals that are increasingly detected in urban-impacted environments, particularly those receiving treated wastewater. PPCPs may have toxicological effects on the macrofauna that are exposed through contaminated water; thus, there is interest in microbially mediated transformations that may degrade PPCPs. This review discusses specific examples of PPCP transformations that may occur in anoxic environments, including O-methylation and O-demethylation.https://f1000research.com/articles/9-130/v1
collection DOAJ
language English
format Article
sources DOAJ
author Abigail W. Porter
Sarah J. Wolfson
Max Häggblom
Lily Y. Young
spellingShingle Abigail W. Porter
Sarah J. Wolfson
Max Häggblom
Lily Y. Young
Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
F1000Research
author_facet Abigail W. Porter
Sarah J. Wolfson
Max Häggblom
Lily Y. Young
author_sort Abigail W. Porter
title Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
title_short Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
title_full Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
title_fullStr Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
title_full_unstemmed Microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
title_sort microbial transformation of widely used pharmaceutical and personal care product compounds [version 1; peer review: 2 approved]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2020-02-01
description Pharmaceutical and personal care products (PPCPs) are commonly used chemicals that are increasingly detected in urban-impacted environments, particularly those receiving treated wastewater. PPCPs may have toxicological effects on the macrofauna that are exposed through contaminated water; thus, there is interest in microbially mediated transformations that may degrade PPCPs. This review discusses specific examples of PPCP transformations that may occur in anoxic environments, including O-methylation and O-demethylation.
url https://f1000research.com/articles/9-130/v1
work_keys_str_mv AT abigailwporter microbialtransformationofwidelyusedpharmaceuticalandpersonalcareproductcompoundsversion1peerreview2approved
AT sarahjwolfson microbialtransformationofwidelyusedpharmaceuticalandpersonalcareproductcompoundsversion1peerreview2approved
AT maxhaggblom microbialtransformationofwidelyusedpharmaceuticalandpersonalcareproductcompoundsversion1peerreview2approved
AT lilyyyoung microbialtransformationofwidelyusedpharmaceuticalandpersonalcareproductcompoundsversion1peerreview2approved
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