Genetic communication by extracellular vesicles is an important mechanism underlying stem cell-based therapy-mediated protection against acute kidney injury

Abstract Stem cell-based therapy appears to be a promising new candidate for acute kidney injury (AKI) management. Traditionally, it has been accepted that the mechanism underlying the regenerative effect of stem cells is based on their paracrine/endocrine activity, including release of bioactive fa...

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Bibliographic Details
Main Authors: Lingfei Zhao, Chenxia Hu, Ping Zhang, Hua Jiang, Jianghua Chen
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1227-8