Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model

Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model

Cerebral infarction is a severe hypoxic ischemic necrosis with accelerated neuronal cell apoptosis in the brain. As a monoclonal antibody against interleukin 6, tocilizumab (TCZ) is widely used in immune diseases, whose function in cerebral infarction has not been studied. This study aims to reveal...

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Bibliographic Details
Main Authors: Shaojun Wang, Jun Zhou, Weijie Kang, Zhaoni Dong, Hezuo Wang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2016-01-01
Series:Bosnian Journal of Basic Medical Sciences
Subjects:
Tocilizumab
cerebral infarction
apoptosis
STAT3
interleukin 6
Online Access:https://bjbms.org/ojs/index.php/bjbms/article/view/853

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