The Effects of the Melatonin Treatment on the Oxidative Stress and Apoptosis in Diabetic Eye and Brain

The Effects of the Melatonin Treatment on the Oxidative Stress and Apoptosis in Diabetic Eye and Brain

Oxidative stress plays an important role in the development of complications in diabetes mellitus. Antioxidant therapy has been thought to decrease oxidative stress. The objective of the present study was to explore the effects of melatonin (MLT) on oxidative stress in diabetic rat eye and brain ti...

Full description

Bibliographic Details
Main Authors:	Tuğba Gürpınar, Nuran Ekerbiçer, Nazan Uysal, Turgay Barut, Figen Tarakçı, M. Ibrahim Tuglu
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1100/2012/498489

Similar Items

Melatonin and L-carnitin improves endothelial disfunction and oxidative stress in Type 2 diabetic rats
by: Derya Selcen Salmanoglu, et al.
Published: (2016-08-01)

Melatonin and oxidative stress
by: J. A. Solís Herruzo, et al.

Melatonin treatment reduces astrogliosis and apoptosis in rats with traumatic brain injury
by: Abdolreza Babaee, et al.
Published: (2015-09-01)

Melatonin and its receptors in the eye
by: James, Karenza
Published: (1996)

Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress
by: Hossam Ebaid, et al.
Published: (2020-01-01)

Analysis of the behaviour of retinal pigment epithelial (RPE) cells in relation to their maintenance in the epithelium during development of the chick eye
by: Tuglu, Mehmet Ibrahim
Published: (1998)

Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy
by: Tingting Jiang, et al.
Published: (2016-01-01)

DNA protective effects of melatonin on oxidative stress in streptozotocin - induced diabetic rats.
by: Selim Sekkin, et al.
Published: (2015-05-01)

Melatonin reverses mitochondria dysfunction and oxidative stress-induced apoptosis of Sudan I-exposed mouse oocytes
by: Chun-Hua Xing, et al.
Published: (2021-12-01)

The influence of melatonin on apoptosis of human neutrophils
by: Sylwia Mańka, et al.
Published: (2019-02-01)

Effects of stem cells applications on oxidative stress and apoptosis during implantation
by: Işıl Aydemir, et al.
Published: (2018-01-01)

Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism
by: Gaoqing Xu, et al.
Published: (2019-08-01)

Dopamine-induced oxidative injury in rat brain: Neuroprotective effect of melatonin
by: Kuei-Feng Chang, et al.
Published: (2005)

Oxidative Stress and Immunosenescence: Therapeutic Effects of Melatonin
by: Javier Espino, et al.
Published: (2012-01-01)

Evaluating the Oxidative Stress in Inflammation: Role of Melatonin
by: Aroha Sánchez, et al.
Published: (2015-07-01)

Melatonin target sites in the brain
by: Aggelopoulos, Nikolaos
Published: (1990)

Melatonin Inhibits Oxidative Stress and Apoptosis in Cryopreserved Ovarian Tissues via Nrf2/HO-1 Signaling Pathway
by: Tie Cheng Sun, et al.
Published: (2020-07-01)

Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells
by: Chih-Chao Chang, et al.
Published: (2018-01-01)

Melatonin alleviates benzo(a)pyrene-induced ovarian corpus luteum dysfunction by suppressing excessive oxidative stress and apoptosis
by: Hanting Xu, et al.
Published: (2021-01-01)

Melatonin protects the heart and pancreas by improving glucose homeostasis, oxidative stress, inflammation and apoptosis in T2DM-induced rats
by: Doaa A. Abdulwahab, et al.
Published: (2021-03-01)

Melatonin Attenuates Contrast-Induced Nephropathy in Diabetic Rats: The Role of Interleukin-33 and Oxidative Stress
by: Didem Onk, et al.
Published: (2016-01-01)

Influence of Circadian Rhythm in the Eye: Significance of Melatonin in Glaucoma
by: Alejandro Martínez-Águila, et al.
Published: (2021-02-01)

Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy
by: Sonia Sifuentes-Franco, et al.
Published: (2018-01-01)

An updated review of mechanistic potentials of melatonin against cancer: pivotal roles in angiogenesis, apoptosis, autophagy, endoplasmic reticulum stress and oxidative stress
by: Saeed Mehrzadi, et al.
Published: (2021-03-01)

Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis.
by: Andrea Janz Moreira, et al.
Published: (2015-01-01)

Effects of Melatonin on the Proliferation and Apoptosis of Sheep Granulosa Cells under Thermal Stress
by: Yao Fu, et al.
Published: (2014-11-01)

Melatonin increases 5-flurouracil-mediated apoptosis of colorectal cancer cells through enhancing oxidative stress and downregulating survivin and XIAP
by: Ainaz Mihanfar, et al.
Published: (2021-07-01)

Melatonin protects rats testes against bleomycin, etoposide, and cisplatin-induced toxicity via mitigating nitro-oxidative stress and apoptosis
by: Mojtaba Moradi, et al.
Published: (2021-06-01)

Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
by: Yonghui Jiang, et al.
Published: (2021-01-01)

Use of Melatonin in Oxidative Stress Related Neonatal Diseases
by: Gabriella D’Angelo, et al.
Published: (2020-06-01)

Melatonin and oxidative stress Melatonia y estrés oxidativo
by: J. A. Solís Herruzo, et al.
Published: (2009-07-01)

Effect of Melatonin Intake on Oxidative Stress Biomarkers in Male Reproductive Organs of Rats under Experimental Diabetes
by: Marina G. Gobbo, et al.
Published: (2015-01-01)

The Effects of Melatonin On The Oxidative Stress , Protein Glycation , Microalbuminuria and Lipid Profile In Type II Diabetes Mellitus
by: Hasan M.H. Alâ€“Mhbashy, et al.
Published: (2017-03-01)

Oxidative injury to the locus coeruleus of rat brain：Neuroprotection of melatonin and vitamin D3
by: Kuen-Bor Chen, et al.
Published: (2003)

Myocardial apoptosis in acute diabetes : role of lipotoxicity and oxidative stress
by: Ghosh, Sanjoy
Published: (2009)

Myocardial apoptosis in acute diabetes : role of lipotoxicity and oxidative stress
by: Ghosh, Sanjoy
Published: (2009)

Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats
by: Samir A. E. Bashandy, et al.
Published: (2021-01-01)

Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells
by: Nan Zhou, et al.
Published: (2019-12-01)

Melatonin attenuates oxidative stress and inflammation of Müller cells in diabetic retinopathy via activating the Sirt1 pathway
by: Yuanyuan Tu, et al.
Published: (2021-05-01)

Melatonin: Awakening the Defense Mechanisms during Plant Oxidative Stress
by: Adil Khan, et al.
Published: (2020-03-01)