Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130)
Summary Cullin-RING ubiquitin ligases (CRLs) mediate the ubiquitination of numerous protein substrates and target them for proteasomal degradation. The function of CRLs is under tight regulation by Cullin-binding proteins. It has been reported that the Spliceosome-associated protein 130 (SAP130/SF3b...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/2/8/838 |