Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer

Abstract Background Tumor mutational burden (TMB) is a promising predictor, which could stratify colorectal cancer (CRC) patients based on the response to immune checkpoint inhibitors (ICIs). MicroRNAs (miRNAs) act as the key regulators of anti-cancer immune response. However, the relationship betwe...

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Bibliographic Details
Main Authors: Lijun Xu, Qing Zheng
Format: Article
Language:English
Published: BMC 2021-02-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:https://doi.org/10.1186/s12957-021-02137-1