Identification and validation of a miRNA-related expression signature for tumor mutational burden in colorectal cancer
Abstract Background Tumor mutational burden (TMB) is a promising predictor, which could stratify colorectal cancer (CRC) patients based on the response to immune checkpoint inhibitors (ICIs). MicroRNAs (miRNAs) act as the key regulators of anti-cancer immune response. However, the relationship betwe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | World Journal of Surgical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12957-021-02137-1 |