Effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations

Effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations

Introduction : The NBN gene product is part of the MRE11/RAD50/ NBN complex, which plays an essential role in genomic stability. In the study we try to answer the question what is the effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with homozygous...

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Bibliographic Details
Main Authors: Jerzy Nowak, Bogna Świątek-Kościelna, Ewelina M. Kałużna, Jolanta Rembowska, Agnieszka Dzikiewicz-Krawczyk, Mariola Zawada, Danuta Januszkiewicz-Lewandowska
Format: Article
Language:English
Published: Termedia Publishing House 2017-01-01
Series:Archives of Medical Science
Subjects:
DNA damage
genetic instability
<I>NBN</I>
nibrin
radiosensitivity
Online Access:https://www.termedia.pl/Effect-of-irradiation-on-DNA-synthesis-NBN-gene-expression-and-chromosomal-stability-in-cells-with-NBN-mutations,19,29240,1,1.html

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https://www.termedia.pl/Effect-of-irradiation-on-DNA-synthesis-NBN-gene-expression-and-chromosomal-stability-in-cells-with-NBN-mutations,19,29240,1,1.html

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