The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam. We hypothesized that there may be genetic variations of the MDR1 gene, based on the response to midazolam.MethodsOne hundred and ninety-three...

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Bibliographic Details
Main Authors: Hyo-Jin Byon, Keun-Suk Park, Yong-Hee Park, Jin-Tae Kim, Chul-Woo Jung, Hee-Soo Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2012-04-01
Series:Korean Journal of Anesthesiology
Subjects:
genetic polymorphism
mdr1
midazolam
Online Access:http://ekja.org/upload/pdf/kjae-62-332.pdf

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