El Tor Biotype Vibrio cholerae Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes

El Tor Biotype Vibrio cholerae Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes

Vibrio cholerae is a Gram-negative enteropathogen causing potentially life-threatening cholera disease outbreaks, for which the World Health Organization currently registers 2–4 million cases and ~100.000 cholera-associated deaths annually worldwide. Genomic Vibrio cholerae research revealed that th...

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Bibliographic Details
Main Authors: Michail Mamantopoulos, Ulrika C. Frising, Tomoko Asaoka, Geert van Loo, Mohamed Lamkanfi, Andy Wullaert
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Vibrio cholerae El Tor biotype
caspase-1
caspase-11
Nlrp3
pyrin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02463/full

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