Comparative study of efficacy of methyldopa vs labetalol in the management of pregnancy induced hypertension in respect to maternal and perinatal outcomes

• Main Author: Bidisha Roychoudhury
• Format: Article
• Language: English
• Published: Makhdoomi Printers 2015-01-01
• Series: Global Journal of Medicine and Public Health
• Subjects: PIH; Methyldopa
• Online Access: http://gjmedph.com/uploads/O5-Vo4No4.pdf

This study was a prospective, comparative study, used to determine & compare the efficacy of treatment with methyldopa vs labetalol with respect to maternal – perinatal benefits and adverse effects. Conducted in the Department of Obstetrics and Gynaecology in Vivekananda Institute of Medical Science, Ramakrishna Mission Seva Pratishthan, a total 425 patients were taken into the study. The patients were divided into two groups by simple random sampling method. They were monitored throughout pregnancy and delivery till 7 days postpartum. The results obtained were divided in 3 sections- Effective BP control, Maternal outcome, Perinatal outcome, which were again divided into three periods – Antepartum, Intrapartum and Postpartum for better elaboration. The study revealed that labetalol helps in quicker and more efficacious control of BP in mothers developing gestational hypertension with chances of developing preeclampsia – eclampsia syndrome.