A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis
The Hill function is commonly used as a building block to model different dynamic patterns found in the response of genetic regulatory circuits within microorganisms and cells. These circuits are characterized by fast response and robustness against unmeasured disturbances. Therefore, microorganisms...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | Mathematical Problems in Engineering |
Online Access: | http://dx.doi.org/10.1155/2015/271216 |
id |
doaj-fab58b1362a04e3b9a598d165609e75f |
---|---|
record_format |
Article |
spelling |
doaj-fab58b1362a04e3b9a598d165609e75f2020-11-25T01:20:39ZengHindawi LimitedMathematical Problems in Engineering1024-123X1563-51472015-01-01201510.1155/2015/271216271216A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability AnalysisJosé Ricardo Pérez-Correa0Gastón Lefranc1Mario Fernández-Fernández2Departamento de Ingeniería Química y Bioprocesos, Pontificia Universidad Católica de Chile, Avenida Vicuña Mackenna 4860, 7820436 Santiago, ChileEscuela de Ingeniería Eléctrica, Pontificia Universidad Católica De Valparaíso, Avenida Brasil 2950, 2340000 Valparaíso, ChileDepartamento de Tecnologías Industriales, Universidad de Talca, Camino a Los Niches km 1, 3440000 Curicó, ChileThe Hill function is commonly used as a building block to model different dynamic patterns found in the response of genetic regulatory circuits within microorganisms and cells. These circuits are characterized by fast response and robustness against unmeasured disturbances. Therefore, microorganisms and cells can survive even if they are subjected to strong changes in their environment. However, as far as we know, the Hill function has not been used before to design process control systems. In this work, the repressor Hill function is applied to control the level of a conic tank. To eliminate the offset, we added integrative action. A local analysis was applied to define stability limits for the control parameters. A cost function that includes the error and the control effort was used to compare the performance of the Hill control against a standard PI and a PID-Dahlin controller.http://dx.doi.org/10.1155/2015/271216 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
José Ricardo Pérez-Correa Gastón Lefranc Mario Fernández-Fernández |
spellingShingle |
José Ricardo Pérez-Correa Gastón Lefranc Mario Fernández-Fernández A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis Mathematical Problems in Engineering |
author_facet |
José Ricardo Pérez-Correa Gastón Lefranc Mario Fernández-Fernández |
author_sort |
José Ricardo Pérez-Correa |
title |
A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis |
title_short |
A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis |
title_full |
A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis |
title_fullStr |
A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis |
title_full_unstemmed |
A New Application of the Hill Repressor Function: Automatic Control of a Conic Tank Level and Local Stability Analysis |
title_sort |
new application of the hill repressor function: automatic control of a conic tank level and local stability analysis |
publisher |
Hindawi Limited |
series |
Mathematical Problems in Engineering |
issn |
1024-123X 1563-5147 |
publishDate |
2015-01-01 |
description |
The Hill function is commonly used as a building block to model different dynamic patterns found in the response of genetic regulatory circuits within microorganisms and cells. These circuits are characterized by fast response and robustness against unmeasured disturbances. Therefore, microorganisms and cells can survive even if they are subjected to strong changes in their environment. However, as far as we know, the Hill function has not been used before to design process control systems. In this work, the repressor Hill function is applied to control the level of a conic tank. To eliminate the offset, we added integrative action. A local analysis was applied to define stability limits for the control parameters. A cost function that includes the error and the control effort was used to compare the performance of the Hill control against a standard PI and a PID-Dahlin controller. |
url |
http://dx.doi.org/10.1155/2015/271216 |
work_keys_str_mv |
AT josericardoperezcorrea anewapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis AT gastonlefranc anewapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis AT mariofernandezfernandez anewapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis AT josericardoperezcorrea newapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis AT gastonlefranc newapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis AT mariofernandezfernandez newapplicationofthehillrepressorfunctionautomaticcontrolofaconictanklevelandlocalstabilityanalysis |
_version_ |
1725132912346529792 |